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A2 - Treating Opioid Dependent Pregnant Patients: Results of the MOTHER Study

Hendree Jones, PhD, Research Triangle Institute International, RTP, NC

Karol Kaltenbach, PhD, Thomas Jefferson University, Philadelphia, PA

This workshop will present neonatal and maternal outcomes of the Maternal Opioid Treatment: Human Experimental Research (MOTHER) project, a seven-site, international, double-blind randomized clinical trial. The presentation will include the comparison of methadone and buprenorphine on the primary outcome measures: number of neonates requiring NAS treatment; peak NAS score; total amount of medication needed to treat NAS; length of hospital stay; and head circumference. Key secondary outcomes presented will include neonatal and maternal drug use treatment and delivery outcomes. The workshop will conclude with a discussion of the historical importance and far-reaching clinical practice and health-policy implications of these data.