Inpatient and outpatient Opioid Treatment Programs (OTPs) have a critical role in prevention of opioid overdose. Patients in OTPs are at higher risk of overdose upon initiation or discontinuation of treatment and with concomitant substance use. Programmatic and other barriers have prevented many OTPs from realizing their potential in regards to patients, staff, and community education; overdose prevention planning; and naloxone distribution. This workshop uses concrete examples of putting state and program-level policies into action in an OTP to prevent opioid overdose and increase naloxone uptake. Ideas and tools for best practices will be discussed and provided.