Methadone 101

  • Laura F. McNicholas, MD, University of Pennsylvania, Philadelphia, PA
  • Kenneth B. Stoller, MD, Johns Hopkins University, Baltimore, MD
  • Yngvild Olsen, MD, Institutes for Behavior Resources, Inc., Baltimore, MD


Methadone maintenance treatment within the setting of comprehensive opioid treatment programs (OTPs) has been available for decades. Yet many clinicians and policymakers do not understand how and why it is effective in treating opioid use disorder (OUD). The presenters will review the basic elements of opioid agonist treatment; examine the pharmacologic aspects of methadone; present initial screening, admission, and assessment techniques; describe associated medical, psychiatric, and substance use conditions associated with OUD; describe the efficacy of methadone maintenance; review other OUD pharmacotherapies; and review the continuum of routine and wraparound services that are provided in OTPs.

*Foundations of MAT

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