So what does all this have to do with methadone maintenance? None of it was known 32 years ago when Dole and Nyswander conceived the idea that a long-acting opiate might stabilize the neurochemistry and behavior of heroin addicts. Now, every professional care-giver who has treated heroin addicts properly with methadone knows how effective this medication can be.

Whether a heroin addict’s reward pathway was defective to begin with, or whether it was altered by the long-term insult of excessive dopamine release, it seems to function normally only if an opiate continuously occupies the mu opioid receptors. This continuous receptor occupancy is the stabilizing factor that permits addicts on methadone to normalize their behavior and to discontinue heroin use. It is, therefore, not correct to think of methadone as a “substitute” for heroin; its totally different pharmacokinetic properties make it, in effect, a completely different drug. It is true that both heroin (morphine) and methadone can occupy the mu opioid receptors. But the steady, stable occupancy by methadone contrasts sharply with the repeated excessive “highs” followed by excessive “lows” with heroin.

Methadone is not an experimental medication. It is more soundly based in biologic science and has been proved in more clinical trials than many drugs we use in modern medicine. It has helped hundreds of thousands of heroin addicts all over the world. It is safe and efficacious. Taken by mouth, it is well absorbed into the circulation, and it occupies the mu opioid receptors in the brain for about 24 hours. Its stabilizing action puts an end to the pattern of alternating “high” and “sick” several times a day that is typical for heroin addicts.

The effectiveness of methadone by mouth permits the addict to discontinue intravenous drug use, thus reducing the risk of hepatitis, AIDS, and other blood-borne infectious diseases. Quitting intravenous drug use is also the first step away from a set of bizarre anti-social behaviors.

When used properly, methadone allows a heroin addict to stop using heroin. It diminishes the craving for heroin, and by producing opioid tolerance it blocks the heroin “high”. Very important, if a patient on methadone does occasionally use heroin, that event need not become a relapse — it can remain a single episode, without significant consequences. In contrast, an abstinent ex-addict can almost never prevent a single “taste” of heroin from leading to a total relapse.

Methadone itself is a therapeutic aid, not a panacea. No magical interventions can stop a heroin addict from using, unless there is some motivation to stop. Thus, methadone must be accompanied by skillful counseling and rehabilitative aid, by psychotherapy as required (comorbidity with other mental illnesses is common), by job training if needed, by family involvement, and so on. Success requires a well-run program with well-trained staff, who understand that heroin addiction is a chronic relapsing disease, and who treat the addict with respect. The primary criterion of success is cessation of heroin use and of other drug abuse, as well as social rehabilitation. Giving up methadone eventually is realistic for some patients, not for others; it is certainly NOT a primary goal of treatment. As the underlying defect in the reward pathway has not been cured, there may well be addicts (we don’t know how many) who will require lifelong maintenance, much as diabetics requires insulin.

Visit the aatod conference website for more details…www.aatodconference.com.

@aatod1984
  • Welcome to the #aatod2024 Conference
  • Welcome to Las Vegas. We invite you to attend this evening’s AATOD Board meeting ➡️ bit.ly/4apbmVt #aatod2024
  • Join us for the highly acclaimed 8-hour clinician’s course which convenes on Sunday, May 19, 2024 ➡️ bit.ly/3UOKtVi
#aatod2024
  • 📰 AATOD Unites Global Leaders in Opioid Use Disorder Treatment for Pivotal Las Vegas Summit 
➡️https://prn.to/3wEvR2G #OUD #somuchmorethanmedication #aatod2024
  • 💻 Welcome Message from Dr. Dinita Smith, Psy.D, MSW - #aatod2024 Conference Chair 

Thank you to our generous Conference Sponsors, Hosts, Exhibitors, Keynote Speakers, Presenters, Volunteers, and the entire Conference Planning Committee.

Online registration is still available. We look forward to welcoming you to Las Vegas!
  • Post & Hashtag 📸 
We would love to hear about your #aatod2024 conference experience on social media.
  • Conference Program Spotlight - Exhibits
The #aatod2024 Conference will attract over 1,600 physicians, social workers, nurses, counselors, program administrators, executive directors, and other treatment providers from many countries. Visit the AATOD Exhibit Hall for networking opportunities, to learn about new products & services and for guidance on how to improve patient treatment ➡️ bit.ly/3yi8T1M.
  • May 7, 2024 = #NationalFentanylAwarenessDay #JustSayKNOW
➡️ fentanylawarenessday.org

As many of you know, the #aatod2024 Conference is just one week away. Our impressive conference program consists of 2 Pre-Conference sessions, 4 Poster Author sessions and 1 Hot Topic Roundtable addressing the urgent problem of illicit fentanyl. These educational sessions are open to all conference attendees. 

Please visit our conference program for more details ➡️ bit.ly/3Ue57Q6
  • You won’t want to miss these 3 POWERFUL Plenary Sessions ready to set the stage in Las Vegas less than 2 weeks. Register today for the #aatod2024 Conference, the world's premier training conference event for the Treatment of Opioid Use Disorder ➡️www.aatodconference.com⬅️
  • 📣 Announcing the AMAZING Line-Up of Plenary Speakers

💻 View the #aatod2024 Conference Video Message from Ann Jamieson, MS,LADC/MH - AATOD’s Plenary Chair.

😊 We couldn’t be more excited about what we have in store for you next week in the spectacular city of Las Vegas where we will convene our conference!

🎤 You will not want to miss the three impressive plenary sessions that have been organized to deliver you extraordinary presentations for your educational purposes. These Plenary Sessions will cover a range of topics that highlight our conference theme, “Treating Opioid Use Disorder: So Much More Than Medication.” We have packed a lot of information into the plenary sessions and are excited to present the policies and strategies in Nevada and nationally.

Join us in Las Vegas by registering for the #aatod2024 Conference ➡️ www.aatodconference.com.
Welcome to the #aatod2024 Conference
1 week ago
View on Instagram |
1/10
Welcome to Las Vegas. We invite you to attend this evening’s AATOD Board meeting ➡️ bit.ly/4apbmVt #aatod2024
Welcome to Las Vegas. We invite you to attend this evening’s AATOD Board meeting ➡️ bit.ly/4apbmVt #aatod2024
1 week ago
View on Instagram |
2/10
Join us for the highly acclaimed 8-hour clinician’s course which convenes on Sunday, May 19, 2024 ➡️ bit.ly/3UOKtVi
#aatod2024
Join us for the highly acclaimed 8-hour clinician’s course which convenes on Sunday, May 19, 2024 ➡️ bit.ly/3UOKtVi #aatod2024
1 week ago
View on Instagram |
3/10
📰 AATOD Unites Global Leaders in Opioid Use Disorder Treatment for Pivotal Las Vegas Summit 
➡️https://prn.to/3wEvR2G #OUD #somuchmorethanmedication #aatod2024
📰 AATOD Unites Global Leaders in Opioid Use Disorder Treatment for Pivotal Las Vegas Summit ➡️https://prn.to/3wEvR2G #OUD #somuchmorethanmedication #aatod2024
2 weeks ago
View on Instagram |
4/10
💻 Welcome Message from Dr. Dinita Smith, Psy.D, MSW - #aatod2024 Conference Chair Thank you to our generous Conference Sponsors, Hosts, Exhibitors, Keynote Speakers, Presenters, Volunteers, and the entire Conference Planning Committee. Online registration is still available. We look forward to welcoming you to Las Vegas!
2 weeks ago
View on Instagram |
5/10
Post & Hashtag 📸 
We would love to hear about your #aatod2024 conference experience on social media.
Post & Hashtag 📸 We would love to hear about your #aatod2024 conference experience on social media.
2 weeks ago
View on Instagram |
6/10
Conference Program Spotlight - Exhibits
The #aatod2024 Conference will attract over 1,600 physicians, social workers, nurses, counselors, program administrators, executive directors, and other treatment providers from many countries. Visit the AATOD Exhibit Hall for networking opportunities, to learn about new products & services and for guidance on how to improve patient treatment ➡️ bit.ly/3yi8T1M.
Conference Program Spotlight - Exhibits The #aatod2024 Conference will attract over 1,600 physicians, social workers, nurses, counselors, program administrators, executive directors, and other treatment providers from many countries. Visit the AATOD Exhibit Hall for networking opportunities, to learn about new products & services and for guidance on how to improve patient treatment ➡️ bit.ly/3yi8T1M.
2 weeks ago
View on Instagram |
7/10
May 7, 2024 = #NationalFentanylAwarenessDay #JustSayKNOW
➡️ fentanylawarenessday.org

As many of you know, the #aatod2024 Conference is just one week away. Our impressive conference program consists of 2 Pre-Conference sessions, 4 Poster Author sessions and 1 Hot Topic Roundtable addressing the urgent problem of illicit fentanyl. These educational sessions are open to all conference attendees. 

Please visit our conference program for more details ➡️ bit.ly/3Ue57Q6
May 7, 2024 = #NationalFentanylAwarenessDay #JustSayKNOW ➡️ fentanylawarenessday.org As many of you know, the #aatod2024 Conference is just one week away. Our impressive conference program consists of 2 Pre-Conference sessions, 4 Poster Author sessions and 1 Hot Topic Roundtable addressing the urgent problem of illicit fentanyl. These educational sessions are open to all conference attendees. Please visit our conference program for more details ➡️ bit.ly/3Ue57Q6
2 weeks ago
View on Instagram |
8/10
You won’t want to miss these 3 POWERFUL Plenary Sessions ready to set the stage in Las Vegas less than 2 weeks. Register today for the #aatod2024 Conference, the world's premier training conference event for the Treatment of Opioid Use Disorder ➡️www.aatodconference.com⬅️
You won’t want to miss these 3 POWERFUL Plenary Sessions ready to set the stage in Las Vegas less than 2 weeks. Register today for the #aatod2024 Conference, the world's premier training conference event for the Treatment of Opioid Use Disorder ➡️www.aatodconference.com⬅️
You won’t want to miss these 3 POWERFUL Plenary Sessions ready to set the stage in Las Vegas less than 2 weeks. Register today for the #aatod2024 Conference, the world's premier training conference event for the Treatment of Opioid Use Disorder ➡️www.aatodconference.com⬅️
You won’t want to miss these 3 POWERFUL Plenary Sessions ready to set the stage in Las Vegas less than 2 weeks. Register today for the #aatod2024 Conference, the world's premier training conference event for the Treatment of Opioid Use Disorder ➡️www.aatodconference.com⬅️
3 weeks ago
View on Instagram |
9/10
📣 Announcing the AMAZING Line-Up of Plenary Speakers 💻 View the #aatod2024 Conference Video Message from Ann Jamieson, MS,LADC/MH - AATOD’s Plenary Chair. 😊 We couldn’t be more excited about what we have in store for you next week in the spectacular city of Las Vegas where we will convene our conference! 🎤 You will not want to miss the three impressive plenary sessions that have been organized to deliver you extraordinary presentations for your educational purposes. These Plenary Sessions will cover a range of topics that highlight our conference theme, “Treating Opioid Use Disorder: So Much More Than Medication.” We have packed a lot of information into the plenary sessions and are excited to present the policies and strategies in Nevada and nationally. Join us in Las Vegas by registering for the #aatod2024 Conference ➡️ www.aatodconference.com.
3 weeks ago
View on Instagram |
10/10

#aatod2024 Conference – Las Vegas

COUNTDOWN

2024 Conference

AATOD, Inc.
225 Varick Street, Suite 402
New York, New York 10014

Contact Us
Phone : 212-566-5555
Email : info@aatod.org

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