SECOND KEY QUESTION: Since withdrawal discomfort is now readily controlled with various medications, so that an addict can be brought without difficulty to an abstinent state, why doesn’t that solve the problem? Why is relapse so common? Is it because of innate deficiencies in the reward pathway, or because chronic exposure to an opiate has caused irreversible changes? In either case, there may be addicts who can not function normally on their own supply of endorphins but require some opiate (like methadone) to occupy the receptors.

We need to know what triggers relapse in an abstinent ex-addict. Relapse is preceded by craving — an irresistible urge to use, often provoked by an environmental cue related to previous use. A cue such as the sight of injection paraphernalia or of a place to buy heroin on the street can not only evoke craving, but can cause measurable physiologic changes like altered pulse, blood pressure, and galvanic skin responses.

A recent study, by researchers at the National Institute on Drug Abuse, concerns craving for cocaine in former cocaine abusers. The method was PET scan, an imaging procedure that shows which areas in the living human brain are activated by certain stimuli. There are two groups of subjects — people who had never used cocaine, and people who had been cocaine abusers in the past but had not used any in recent months. Two kinds of cue were presented on video tape — a neutral one (such as a pastoral scene), and a cocaine-related one (such as injection equipment). Subjects who had never used cocaine showed no unusual brain activity when exposed to either kind of cue. Subjects who had abused cocaine in the past were not affected at all by a neutral cue; but they responded very differently to a cocaine-related cue. Intense craving was provoked, and specific brain areas lit up on the PET scan — areas in parts of the brain (frontal cortex and amygdala) that are known to be associated with emotional memories and craving.

I tell you about this experiment because it shows clearly that in the subjects with previous heavy exposure to cocaine, certain brain regions had been altered by the chronic use of the addictive drug. And it also shows which brain areas are specifically involved in the craving that leads to relapse. Most important for us, it points the way to future similar research with heroin addicts, using brain imaging techniques — an exciting prospect that was only a dream just a few years ago.

Source:
Neurobiology of Heroin Addiction and of Methadone Treatment
By: Avram Goldstein, M.D.
Professor Emeritus of Pharmacology, Stanford University

Visit the aatod conference website for more details…www.aatodconference.com.

@aatod1984
  • Welcome to Las Vegas. We invite you to attend this evening’s AATOD Board meeting ➡️ bit.ly/4apbmVt #aatod2024
  • Join us for the highly acclaimed 8-hour clinician’s course which convenes on Sunday, May 19, 2024 ➡️ bit.ly/3UOKtVi
#aatod2024
  • 📰 AATOD Unites Global Leaders in Opioid Use Disorder Treatment for Pivotal Las Vegas Summit 
➡️https://prn.to/3wEvR2G #OUD #somuchmorethanmedication #aatod2024
  • 💻 Welcome Message from Dr. Dinita Smith, Psy.D, MSW - #aatod2024 Conference Chair 

Thank you to our generous Conference Sponsors, Hosts, Exhibitors, Keynote Speakers, Presenters, Volunteers, and the entire Conference Planning Committee.

Online registration is still available. We look forward to welcoming you to Las Vegas!
  • Post & Hashtag 📸 
We would love to hear about your #aatod2024 conference experience on social media.
  • Conference Program Spotlight - Exhibits
The #aatod2024 Conference will attract over 1,600 physicians, social workers, nurses, counselors, program administrators, executive directors, and other treatment providers from many countries. Visit the AATOD Exhibit Hall for networking opportunities, to learn about new products & services and for guidance on how to improve patient treatment ➡️ bit.ly/3yi8T1M.
  • May 7, 2024 = #NationalFentanylAwarenessDay #JustSayKNOW
➡️ fentanylawarenessday.org

As many of you know, the #aatod2024 Conference is just one week away. Our impressive conference program consists of 2 Pre-Conference sessions, 4 Poster Author sessions and 1 Hot Topic Roundtable addressing the urgent problem of illicit fentanyl. These educational sessions are open to all conference attendees. 

Please visit our conference program for more details ➡️ bit.ly/3Ue57Q6
  • You won’t want to miss these 3 POWERFUL Plenary Sessions ready to set the stage in Las Vegas less than 2 weeks. Register today for the #aatod2024 Conference, the world's premier training conference event for the Treatment of Opioid Use Disorder ➡️www.aatodconference.com⬅️
  • 📣 Announcing the AMAZING Line-Up of Plenary Speakers

💻 View the #aatod2024 Conference Video Message from Ann Jamieson, MS,LADC/MH - AATOD’s Plenary Chair.

😊 We couldn’t be more excited about what we have in store for you next week in the spectacular city of Las Vegas where we will convene our conference!

🎤 You will not want to miss the three impressive plenary sessions that have been organized to deliver you extraordinary presentations for your educational purposes. These Plenary Sessions will cover a range of topics that highlight our conference theme, “Treating Opioid Use Disorder: So Much More Than Medication.” We have packed a lot of information into the plenary sessions and are excited to present the policies and strategies in Nevada and nationally.

Join us in Las Vegas by registering for the #aatod2024 Conference ➡️ www.aatodconference.com.
  • Register for the #aatod2024 Conference ➡️ www.aatodconference.com

⭐️ Conference Program Spotlight ⭐️
We know that opioid use disorder (OUD) knows no geographic boundaries. And, while there are countless initiatives, projects, policy reviews, opportunities, and challenges here in the United States, others around the world are facing and dealing with these same issues as well as successes that will be shared at the conference. 
 
Because we believe it is important and imperative to understand the good and essential work that is being done world-wide, Dr Maremmani and Mike Rizzi (AATOD International Chair) invite you to not only come to the conference but to join us at our Sunday (5/19) International Symposium. Respected international colleagues will address responses and findings related to treatment, recovery, and research in their countries. There will also be a special International Workshop on Tuesday, 5/21.
Welcome to Las Vegas. We invite you to attend this evening’s AATOD Board meeting ➡️ bit.ly/4apbmVt #aatod2024
Welcome to Las Vegas. We invite you to attend this evening’s AATOD Board meeting ➡️ bit.ly/4apbmVt #aatod2024
2 days ago
View on Instagram |
1/10
Join us for the highly acclaimed 8-hour clinician’s course which convenes on Sunday, May 19, 2024 ➡️ bit.ly/3UOKtVi
#aatod2024
Join us for the highly acclaimed 8-hour clinician’s course which convenes on Sunday, May 19, 2024 ➡️ bit.ly/3UOKtVi #aatod2024
3 days ago
View on Instagram |
2/10
📰 AATOD Unites Global Leaders in Opioid Use Disorder Treatment for Pivotal Las Vegas Summit 
➡️https://prn.to/3wEvR2G #OUD #somuchmorethanmedication #aatod2024
📰 AATOD Unites Global Leaders in Opioid Use Disorder Treatment for Pivotal Las Vegas Summit ➡️https://prn.to/3wEvR2G #OUD #somuchmorethanmedication #aatod2024
4 days ago
View on Instagram |
3/10
💻 Welcome Message from Dr. Dinita Smith, Psy.D, MSW - #aatod2024 Conference Chair Thank you to our generous Conference Sponsors, Hosts, Exhibitors, Keynote Speakers, Presenters, Volunteers, and the entire Conference Planning Committee. Online registration is still available. We look forward to welcoming you to Las Vegas!
4 days ago
View on Instagram |
4/10
Post & Hashtag 📸 
We would love to hear about your #aatod2024 conference experience on social media.
Post & Hashtag 📸 We would love to hear about your #aatod2024 conference experience on social media.
5 days ago
View on Instagram |
5/10
Conference Program Spotlight - Exhibits
The #aatod2024 Conference will attract over 1,600 physicians, social workers, nurses, counselors, program administrators, executive directors, and other treatment providers from many countries. Visit the AATOD Exhibit Hall for networking opportunities, to learn about new products & services and for guidance on how to improve patient treatment ➡️ bit.ly/3yi8T1M.
Conference Program Spotlight - Exhibits The #aatod2024 Conference will attract over 1,600 physicians, social workers, nurses, counselors, program administrators, executive directors, and other treatment providers from many countries. Visit the AATOD Exhibit Hall for networking opportunities, to learn about new products & services and for guidance on how to improve patient treatment ➡️ bit.ly/3yi8T1M.
6 days ago
View on Instagram |
6/10
May 7, 2024 = #NationalFentanylAwarenessDay #JustSayKNOW
➡️ fentanylawarenessday.org

As many of you know, the #aatod2024 Conference is just one week away. Our impressive conference program consists of 2 Pre-Conference sessions, 4 Poster Author sessions and 1 Hot Topic Roundtable addressing the urgent problem of illicit fentanyl. These educational sessions are open to all conference attendees. 

Please visit our conference program for more details ➡️ bit.ly/3Ue57Q6
May 7, 2024 = #NationalFentanylAwarenessDay #JustSayKNOW ➡️ fentanylawarenessday.org As many of you know, the #aatod2024 Conference is just one week away. Our impressive conference program consists of 2 Pre-Conference sessions, 4 Poster Author sessions and 1 Hot Topic Roundtable addressing the urgent problem of illicit fentanyl. These educational sessions are open to all conference attendees. Please visit our conference program for more details ➡️ bit.ly/3Ue57Q6
1 week ago
View on Instagram |
7/10
You won’t want to miss these 3 POWERFUL Plenary Sessions ready to set the stage in Las Vegas less than 2 weeks. Register today for the #aatod2024 Conference, the world's premier training conference event for the Treatment of Opioid Use Disorder ➡️www.aatodconference.com⬅️
You won’t want to miss these 3 POWERFUL Plenary Sessions ready to set the stage in Las Vegas less than 2 weeks. Register today for the #aatod2024 Conference, the world's premier training conference event for the Treatment of Opioid Use Disorder ➡️www.aatodconference.com⬅️
You won’t want to miss these 3 POWERFUL Plenary Sessions ready to set the stage in Las Vegas less than 2 weeks. Register today for the #aatod2024 Conference, the world's premier training conference event for the Treatment of Opioid Use Disorder ➡️www.aatodconference.com⬅️
You won’t want to miss these 3 POWERFUL Plenary Sessions ready to set the stage in Las Vegas less than 2 weeks. Register today for the #aatod2024 Conference, the world's premier training conference event for the Treatment of Opioid Use Disorder ➡️www.aatodconference.com⬅️
2 weeks ago
View on Instagram |
8/10
📣 Announcing the AMAZING Line-Up of Plenary Speakers 💻 View the #aatod2024 Conference Video Message from Ann Jamieson, MS,LADC/MH - AATOD’s Plenary Chair. 😊 We couldn’t be more excited about what we have in store for you next week in the spectacular city of Las Vegas where we will convene our conference! 🎤 You will not want to miss the three impressive plenary sessions that have been organized to deliver you extraordinary presentations for your educational purposes. These Plenary Sessions will cover a range of topics that highlight our conference theme, “Treating Opioid Use Disorder: So Much More Than Medication.” We have packed a lot of information into the plenary sessions and are excited to present the policies and strategies in Nevada and nationally. Join us in Las Vegas by registering for the #aatod2024 Conference ➡️ www.aatodconference.com.
2 weeks ago
View on Instagram |
9/10
Register for the #aatod2024 Conference ➡️ www.aatodconference.com

⭐️ Conference Program Spotlight ⭐️
We know that opioid use disorder (OUD) knows no geographic boundaries. And, while there are countless initiatives, projects, policy reviews, opportunities, and challenges here in the United States, others around the world are facing and dealing with these same issues as well as successes that will be shared at the conference. 
 
Because we believe it is important and imperative to understand the good and essential work that is being done world-wide, Dr Maremmani and Mike Rizzi (AATOD International Chair) invite you to not only come to the conference but to join us at our Sunday (5/19) International Symposium. Respected international colleagues will address responses and findings related to treatment, recovery, and research in their countries. There will also be a special International Workshop on Tuesday, 5/21.
Register for the #aatod2024 Conference ➡️ www.aatodconference.com ⭐️ Conference Program Spotlight ⭐️ We know that opioid use disorder (OUD) knows no geographic boundaries. And, while there are countless initiatives, projects, policy reviews, opportunities, and challenges here in the United States, others around the world are facing and dealing with these same issues as well as successes that will be shared at the conference. Because we believe it is important and imperative to understand the good and essential work that is being done world-wide, Dr Maremmani and Mike Rizzi (AATOD International Chair) invite you to not only come to the conference but to join us at our Sunday (5/19) International Symposium. Respected international colleagues will address responses and findings related to treatment, recovery, and research in their countries. There will also be a special International Workshop on Tuesday, 5/21.
2 weeks ago
View on Instagram |
10/10

#aatod2024 Conference – Las Vegas

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2024 Conference

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